PReS13-SPK-1082: Catastrophic antiphospholipid syndrome

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PReS13-SPK-1082: Catastrophic antiphospholipid syndrome

In the 1980’s, isolated case reports appeared in the world literature documenting patients who appeared to suffer from an often fatal complication associated with the demonstration of antiphospholipid antibodies (aPL). The clinical picture comprised widespread multi-organ thrombosis and consequent organ failure and was referred to by the authors as a “devastating non-inflammatory vasculopathy”,...

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PReS13-SPK-1592: Pediatric aspects of antiphospholipid syndrome

Introduction The antiphospholipid antibody syndrome (APS) is a multisystemic autoimmune disease characterized by thromboembolic events, pregnancy morbidity, hematologic, dermatologic, neurologic and other manifestations in the presence of elevated titers of antiphospholipid antibodies (aPL). In recent years, APS has been increasingly recognized in various pediatric autoimmune and nonautoimmune ...

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[Catastrophic antiphospholipid syndrome: CAPS].

Antiphospholipid syndrome (APS) is well known as an autoimmune thrombotic syndrome with recurrent thromboses. In APS, thromboses occurs both artery and vein, and from large to micro vessels. In contrast, so called catastrophic antiphospholipid syndrome, CAPS, develops multiple thromboses at microvessels mainly within a few weeks and induces to poor prognosis. CAPS often occurs in patients with ...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-s2-i10